Study: Fully Vaccinated are More Likely to Carry More Resistant and More Infectious Variants

A recent study published on medRxiv shows that fully vaccinated people are more likely to carry more resistant and more infectious variants.

Though the data on more infectious variants has low statistical significance, the results are in line with other studies showing similar results.

From the study:

“Fully vaccinated were more likely than unvaccinated persons to be infected by variants carrying mutations associated with decreased antibody neutralization (L452R, L452Q, E484K, and/or F490S) (78% versus 48%, p = 1.96e-08), but not by those associated with increased infectivity (L452R and/or N501Y) (85% versus 77%, p = 0.092).”

“Differences in viral loads were non-significant between unvaccinated and fully vaccinated persons overall (p = 0.99)”

“… symptomatic vaccine breakthrough infections had similar viral loads to unvaccinated infections (p = 0.64).”

The study goes on to conclude that the predominance of immune-evading variants among breakthrough cases indicates selective pressure for immune-resistant variants locally over time ‘in the vaccinated population’ concurrent with ongoing viral circulation in the community.

“In summary, our results reveal that selection pressure in a highly vaccinated community (>71% fully vaccinated as of early August 2021) favors more infectious, antibody-resistant VOCs such as the gamma and delta variants, and that high-titer symptomatic post-vaccination infections may be a contributor to viral spread.”

A board-certified physician in internal medicine, Dr Peter Cullough, recently brought attention to another study that is alarming many scientists.

A preprint paper by the prestigious Oxford University Clinical Research Group, which was published on August 10th in The Lancet, found that fully vaccinated individuals carry 251 times the viral load of COVID-19.

“Viral loads of breakthrough Delta variant infection cases were 251 times higher than those of cases infected with old strains detected between March-April 2020.”

According to the study, the vaccines seemingly allow vaccinated individuals to carry unusually high viral loads without becoming ill at least at first, transforming them into superspreaders who will become symptomatic later on.

Many experts are asking if this is the cause of the unprecedented summertime surge in cases many nations are seeing. If asymptomatic spread historically is never the driver of the spread of viruses due to eventual symptomatic patients remaining indoors, what happens when people stay asymptomatic for longer?

Other experts are wondering if these results have something to do with the unprecedented rise in cases and hospitalizations in countries that have a near 100% vaccination rate.

Israel for example, has among the world’s highest levels of vaccination for COVID-19, with 80% of those 12 and older fully vaccinated, the vast majority with the Pfizer vaccine. Yet, the country is now recording one of the world’s highest infection rates and it’s recommended that Americans forgo travel to the country.

More than half of the cases in Israel, and over 60% of the hospitalizations for severe COVID cases are in fully vaccinated people.

study published Sept. 30, in the peer-reviewed European Journal of Epidemiology found “no discernible relationship” between the percentage of the population fully vaccinated and new COVID cases.

In fact, the study found the most fully vaccinated nations had the highest number of new COVID cases, based on the researchers’ analysis of emerging data during a seven-day period in September.

The authors said the sole reliance on vaccination as a primary strategy to mitigate COVID-19 and its adverse consequences “needs to be re-examined,” especially considering the Delta (B.1.617.2) variant and the likelihood of future variants.

“Other pharmacological and non-pharmacological interventions may need to be put in place alongside increasing vaccination rates. Such course correction, especially with regards to the policy narrative, becomes paramount with emerging scientific evidence on real-world effectiveness of the vaccines.”

Israel had the highest COVID cases per 1 million people during the seven-day period.

Another study published in The Lancet shows that efficacy for the Pfizer vaccine drops below 50% after just five months.

The study which was conducted between Dec 14, 2020, and Aug 8, 2021, included 4,920,549 individuals assessed for eligibility. The study also found low efficacy against hospitalizations after 6 months.

“Results provide support for high effectiveness of BNT162b2 against hospital admissions up until around 6 months after being fully vaccinated.”

The results of these studies and others are likely the reason why the Biden administration along with Biden’s chief medical adviser Dr Fauci recently recommended mandatory booster shots for the general population twice a year.

According to a recent report in the New York Post, President Biden said he and Dr. Anthony Fauci discussed requiring COVID-19 booster shots every five months rather than every eight as previously anticipated.

It is also most likely the reason why the CEO of BioNTech, Uğur Şahin, said recently that brand new Covid-19 vaccines will be necessary by mid-2022 to combat the ‘next generation’ of virus strains.

“This year, [a different vaccine] is completely unneeded. But by mid-next year, it could be a different situation,” Sahin said, adding that “tailored” versions of current vaccines would be needed to specifically target the new strains that emerge.

“This virus will stay, and the virus will further adapt,” he said.

The World Health Organization recently echoed the second half of this statement saying the COVID vaccines won’t end the pandemic, and the world must now ‘gradually adapt strategy’ to cope with the inevitable spread of the virus.

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